Biotechnology

Athira Pharma Showcases Neuroprotective Properties of Fosgonimeton in Alzheimer's Disease Models

Published November 16, 2023

Athira Pharma, Inc. ATHA, a pioneer in biopharmaceutical development with a focus on inventing novel small molecules to combat neurodegenerative diseases, recently put forth compelling preclinical data regarding its leading compound, Fosgonimeton. The data was showcased at the prestigious Society for Neuroscience Annual Meeting 2023, casting a promising light on Fosgonimeton's potential role in protecting neuronal health against the insidious effects of amyloid-beta peptides, widely implicated in Alzheimer's disease.

Understanding the Impact of Amyloid-Beta

In Alzheimer's disease, amyloid-beta peptides accumulate to form plaques, a hallmark of the condition that leads to neuronal damage and subsequent cognitive decline. Fosgonimeton aims to arrest the neurodegenerative process by shielding neurons from these amyloid-beta-induced pathological changes and curtailing the accompanying neuroinflammation—all of which were elegantly demonstrated through preclinical models.

Fosgonimeton: A Beacon of Hope for Neurodegeneration

Operating from Bothell, Washington, ATHA's mission to restore neuronal health has taken a significant step forward with these preclinical outcomes. Fosgonimeton, by safeguarding neurons and potentially halting neurodegradation, places Athira Pharma at the forefront of the fight against Alzheimer's disease. As a late-stage biopharmaceutical player, these results fuel the momentum for Fosgonimeton's journey towards becoming a viable therapeutic option for patients grappling with neurodegenerative conditions.

Athira, Fosgonimeton, Alzheimer's